Endocrine Abstracts

Objective: 18F-FDG-avid differentiated thyroid cancers (DTC) have been known to behave more aggressively, especially in metastatic sites (flip-flop phenomenon). However, the clinical behaviour of DTC detected incidentally by FDG–PET (PET incidentaloma) has been sparsely reported. We wanted to know whether flip–flop phenomenon is applicable in PET incidentalomas.Methods: 165 DTC patients who underwent thyroid surgery and had pre-operative FDG&#1...

Background: The risk of thyroid cancer in large thyroid nodules greater than 4 cm has been reported to be increased. Some authors insist that diagnostic lobectomy should be performed in patients with large thyroid nodules, irrespective of fine needle aspiration cytology (FNA) results. However, consensus on that matter has not been met. We wanted to investigate the risk of thyroid malignancy according to the size of the thyroid nodules, based on FNA results.<p class="abstex...

Acromegaly is associated with a range of comorbidities, including cardiovascular disease, diabetes, hypertension and sleep apnea. Bony overgrowth and soft tissue thickening not only cause typical external features of acromegaly, but also debilitating musculoskeletal aches. Recently, a few papers reported auditory complications of acromegaly, but there has been no report on narrowing of the external auditory canal as a complication of acromegaly. A 58-year-old acromegalic patie...

Objective: In subclinical Cushing’s syndrome (SC), it is assumed that glucocorticoid production is insufficient to cause a clinically recognizable syndrome. Differences in hormonal levels or recovery time of the hypothalamic–pituitary–adrenocortical (HPA) axis after adrenalectomy between patients with overt Cushing’s syndrome (OC) and SC remain unknown.Design and patients: Thirty seven patients (ten were OC and 27 were SC) with adrena...

Background: Fixed-dose radioactive iodine therapy (RAI) is one of the standard therapy for Graves’ disease (GD). However, optimal RAI dose to achieve hypothyroidism in GD has been controversial.Methods: The clinical outcome of 124 patients with GD treated with a RAI between Apr. 2004 and Dec. 2014 was analyzed retrospectively. Responder group was defined as patients who were rendered hypothyroid by the RAI. Thyroid volume (TV) was assessed with sono...